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Mrs. Kreiselman, Biology



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DNA Technology

Here you will find links to animation, tutorials, articles in the followign 
topics:
1)DNA fingerprining
a. Techniques
b. Forensic use
c. Restriction and Electrophoresis

2)Genetic Engineering
a. Genetically engineered plants
b. Comparison with selective breeding
c. Transformation of bacteria, plants. 

3) Cloning

4) Stem Cell Research

Standard 5c: Students know how genetic engineering (biotechnology) is used 
to produce novel biomedical and agricultural products. 

*5d: Students know how basic DNA technology (restriction digestion by 
endonucleases, gel electrophoresis, ligation, and transformation) is used to 
construct recombinant DNA molecules.
 
*5e: Students know how exogenous DNA can be inserted into bacterial cells to 
alter their genetic makeup and support expression of new protein products.
 
DNA Detective: Interactive Website for the procedures of Forensic DNA 
testing.
http://www.dnalc.org/ddnalc/resources/shockwave/dnadetective.html

 
 
Lewport (They did it again!) - great animation with text of restriction and 
DNA electrophoresis analysis.
http://www.lewport.wnyric.org/jwanamaker/animations/Chrom&Elpho.html

 
 
Animation of making transgentic plants.
http://www-class.unl.edu/biochem/gp2/m_biology/animation/m_animations/overview1.swf

 
 
DNA profiling interactive - will help you see a common application of 
restriction analysis and DNA gel electrophoresis. And it's fun!
http://www.biotechnology.gov.au/BiotechnologyOnline/interactives/dna_profile_interactive.htm

 
 
Background information about Forensic DNA Evidence
http://www.ojp.usdoj.gov/nij/dna_evbro/index.html

 
 
Great interactive showing how to splice a gene into a plasmid using 
restriction sites.
http://www.biotechnology.gov.au/BiotechnologyOnline/interactives/gene_splicing_interactive.htm

 
 
"Harvest of Fear"! A full 
transcript of the film "Harvest of Fear".
http://www.pbs.org/wgbh/harvest/etc/script.html

 
 
Try this interactive animation to compare selective 
breeding with genetic engineering.. (based on the NOVA film "Harvest of 
Fear")
http://www.pbs.org/wgbh/harvest/engineer/

 
 
From Arizona University - tutorial on trasnformation
http://www.biology.arizona.edu/molecular_bio/problem_sets/Recombinant_DNA_Technology/05t.html

 
 
Gel electrophoresis of proteins - interactive animation. (a bit beyond what 
you need to know, but the DNA part is useful)
http://www.shsu.edu/%7Echm_tgc/sounds/flashfiles/GE.swf

 
 
Why Files - A discussion about Genetically Engineered Crops - Is it Wise to 
make them?
http://whyfiles.org/062ag_gene_eng/index.html

 
 
An interactive tutorial and quiz about RFLP (Restriction Fragment Length 
Polymorphism) and its use for identification.
http://www.biology.arizona.edu/human_bio/problem_sets/DNA_forensics_1/DNA_forensics.html

 
 
USED IN CLASS: Animation of DNA technologies. Try out the ones about 
electrophoresis, restriction/ligation, transformation1, model organisms.
http://www.dnalc.org/ddnalc/resources/animations.html

 
 
DNA Fingerprinting - good background, both technical and historical
http://www.bergen.org/AAST/Projects/Gel/fingprint1.htm

 
 
From NOVA - a great site about forensic DNA testing. Just an example - look 
how long the list is of people that were wrongly incarcerated and aquitted 
only by DNA evidence!
http://www.pbs.org/wgbh/nova/sheppard/cleared.html

 
 
Great Interactive Animations of making a recombinant plasmid DNA.
http://www.biotechnologyonline.gov.au/biotec/cutpaste.cfm

 
 
How DNA Evidence Works - Great Material form HowStuffWorks.com DON'T MISS!In 
fact - check out the entire http://www.howstuffworks.com/csi.htm.
http://people.howstuffworks.com/dna-evidence7.htm

 
 
How CLONING works!
http://science.howstuffworks.com/cloning.htm

 
 
A timeline about cloning - not the onloy one in the market, but pretty up to 
date. Gives a perspective about cloning of pet and farm animals, as well as 
of endangered species.
http://www.savingsandclone.com/cloning/timeline.html

 
 
Another cloning time-line with good articles attached
http://www.biology.iupui.edu/biocourses/Biol540/2background2k5.html

 
 
All you wanted to know about stem cells in an interactive animation, short 
aritcles and more. Great!
http://gslc.genetics.utah.edu/units/stemcells/

 
 
Virtual LABS - Shpwing a variety of uses of DNA technology for disease 
detection, immunology, learning about a heart disease and more!
http://www.hhmi.org/biointeractive/vlabs/index.html

 
 
From the Human Genome Project - DNA techniques
http://homepage.smc.edu/hgp/descrip.htm

 
 
WebLab: DNA Fingerprinting
http://www2.edc.org/weblabs/DNAFingerprinting/DNAFingerprintingMenu.html

 
 
DNA testing for zoologists
http://www.zoologix.com/zoo/index.htm

 
 
Simulation of DNA Fingerprinting
http://www.koshlandsciencemuseum.org/exhibitdna/crim05activity.jsp

 
 
Human Genome Project - Overall infortmation and VERY interesting facts!
(This is the source for the honors' project fall 2007-8).
http://www.ornl.gov/sci/techresources/Human_Genome/project/info.shtml#how

 

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Last Modified: Monday December 03 2007
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