Here you will find links to animation, tutorials, articles in the followign
topics:
1)DNA fingerprining
a. Techniques
b. Forensic use
c. Restriction and Electrophoresis
2)Genetic Engineering
a. Genetically engineered plants
b. Comparison with selective breeding
c. Transformation of bacteria, plants.
3) Cloning
4) Stem Cell Research
Standard 5c: Students know how genetic engineering (biotechnology) is used
to produce novel biomedical and agricultural products.
*5d: Students know how basic DNA technology (restriction digestion by
endonucleases, gel electrophoresis, ligation, and transformation) is used to
construct recombinant DNA molecules.
*5e: Students know how exogenous DNA can be inserted into bacterial cells to
alter their genetic makeup and support expression of new protein products.
DNA Detective: Interactive Website for the procedures of Forensic DNA
testing.
http://www.dnalc.org/ddnalc/resources/shockwave/dnadetective.html
Lewport (They did it again!) - great animation with text of restriction and
DNA electrophoresis analysis.
http://www.lewport.wnyric.org/jwanamaker/animations/Chrom&Elpho.html
Animation of making transgentic plants.
http://www-class.unl.edu/biochem/gp2/m_biology/animation/m_animations/overview1.swf
DNA profiling interactive - will help you see a common application of
restriction analysis and DNA gel electrophoresis. And it's fun!
http://www.biotechnology.gov.au/BiotechnologyOnline/interactives/dna_profile_interactive.htm
Background information about Forensic DNA Evidence
http://www.ojp.usdoj.gov/nij/dna_evbro/index.html
Great interactive showing how to splice a gene into a plasmid using
restriction sites.
http://www.biotechnology.gov.au/BiotechnologyOnline/interactives/gene_splicing_interactive.htm
"Harvest of Fear"! A full
transcript of the film "Harvest of Fear".
http://www.pbs.org/wgbh/harvest/etc/script.html
Try this interactive animation to compare selective
breeding with genetic engineering.. (based on the NOVA film "Harvest of
Fear")
http://www.pbs.org/wgbh/harvest/engineer/
From Arizona University - tutorial on trasnformation
http://www.biology.arizona.edu/molecular_bio/problem_sets/Recombinant_DNA_Technology/05t.html
Gel electrophoresis of proteins - interactive animation. (a bit beyond what
you need to know, but the DNA part is useful)
http://www.shsu.edu/%7Echm_tgc/sounds/flashfiles/GE.swf
Why Files - A discussion about Genetically Engineered Crops - Is it Wise to
make them?
http://whyfiles.org/062ag_gene_eng/index.html
An interactive tutorial and quiz about RFLP (Restriction Fragment Length
Polymorphism) and its use for identification.
http://www.biology.arizona.edu/human_bio/problem_sets/DNA_forensics_1/DNA_forensics.html
USED IN CLASS: Animation of DNA technologies. Try out the ones about
electrophoresis, restriction/ligation, transformation1, model organisms.
http://www.dnalc.org/ddnalc/resources/animations.html
DNA Fingerprinting - good background, both technical and historical
http://www.bergen.org/AAST/Projects/Gel/fingprint1.htm
From NOVA - a great site about forensic DNA testing. Just an example - look
how long the list is of people that were wrongly incarcerated and aquitted
only by DNA evidence!
http://www.pbs.org/wgbh/nova/sheppard/cleared.html
Great Interactive Animations of making a recombinant plasmid DNA.
http://www.biotechnologyonline.gov.au/biotec/cutpaste.cfm
How DNA Evidence Works - Great Material form HowStuffWorks.com DON'T MISS!In
fact - check out the entire http://www.howstuffworks.com/csi.htm.
http://people.howstuffworks.com/dna-evidence7.htm
How CLONING works!
http://science.howstuffworks.com/cloning.htm
A timeline about cloning - not the onloy one in the market, but pretty up to
date. Gives a perspective about cloning of pet and farm animals, as well as
of endangered species.
http://www.savingsandclone.com/cloning/timeline.html
Another cloning time-line with good articles attached
http://www.biology.iupui.edu/biocourses/Biol540/2background2k5.html
All you wanted to know about stem cells in an interactive animation, short
aritcles and more. Great!
http://gslc.genetics.utah.edu/units/stemcells/
Virtual LABS - Shpwing a variety of uses of DNA technology for disease
detection, immunology, learning about a heart disease and more!
http://www.hhmi.org/biointeractive/vlabs/index.html
From the Human Genome Project - DNA techniques
http://homepage.smc.edu/hgp/descrip.htm
WebLab: DNA Fingerprinting
http://www2.edc.org/weblabs/DNAFingerprinting/DNAFingerprintingMenu.html
DNA testing for zoologists
http://www.zoologix.com/zoo/index.htm
Simulation of DNA Fingerprinting
http://www.koshlandsciencemuseum.org/exhibitdna/crim05activity.jsp
Human Genome Project - Overall infortmation and VERY interesting facts!
(This is the source for the honors' project fall 2007-8).
http://www.ornl.gov/sci/techresources/Human_Genome/project/info.shtml#how